FEATURE | APRIL 27, 2015
Study of transgenic mouse model shows chronic vitamin C deficiency leads to structural weakness of blood vessel walls, causing atherosclerotic development
April 27, 2015 — Scientific confirmation has just been published in the American Journal of Cardiovascular Disease that atherosclerosis, the underlying process of heart attacks and strokes, is generally not caused by high cholesterol blood levels. It is rather the result of a structural weakness of the blood vessel walls caused by chronic deficiency of ascorbate (vitamin C).
Heart attacks, strokes and other forms of cardiovascular disease are the single largest disease on our planet with more than 17 million deaths each year. The continuation of this disease in epidemic proportions proves that its true nature has not yet been sufficiently understood. Moreover, the current hypothesis that high cholesterol levels in blood triggers cardiovascular disease cannot answer the most basic question of cardiology: Cholesterol has the same concentration in both arteries and veins. So why do atherosclerotic plaques occur only in arteries – but not in veins? Moreover, why do they develop almost always in the few inches of coronary arteries – but rarely in other organs? Or why is atherosclerosis, a hallmark of the human race, basically unknown in animal species?
Researchers from the Dr. Rath Research Institute in California developed a unique animal model. It is a transgenic mouse that resembles human metabolism in its key aspects, the inability to produce vitamin C and, at the same time, the synthesis of human Lipoprotein(a) – a variant of low-density-lipoprotein (LDL). Using this animal model they demonstrated that atherosclerosis, generally, starts with a dietary depletion of vitamin C and the ensuing structural weakness of the artery walls. This metabolic condition results in an increase in serum Lipoprotein(a) levels and its accumulation in the vascular wall that parallels atherosclerotic lesion development.
This study confirms the scientific concept published in 1990 in the 'Proceedings of the National Academy of Sciences, USA' by Matthias Rath, M.D., together with two-time Nobel Prize winner Linus Pauling, M.D. They proposed that Lipoprotein(a) is a repair molecule that functions as a surrogate for vitamin C in the impaired vascular wall.
The most fascinating aspect of this animal model is the fact that it reproduces a genetic switch, the disappearance of vitamin C to the appearance of Lipoprotein(a), from about 40 million years ago. It proves the concept that a distinct event during the evolution of man can explain the susceptibility of modern man to cardiovascular disease.
For more information: www.ajcd.us
DID YOU KNOW ?
Back in 1989, Double Nobel Prize winning scientist Linus Pauling recognized and announced the cause of coronary heart and all cardiovascular disease as a high dose vitamin C and collagen deficiency and invented a remarkably effective therapy for the prevention and removal of arterial plaque? If not, you certainly aren't alone.
Dr. Pauling's work was well documented (see links below) and submitted to mainstream medical journals for publication but was rejected except by alternative medical journals with a much smaller audience. As a result, the American public has remained largely in the dark and millions of lives have been needlessly lost to heart attack, aneurysm, stroke, and other forms of cardiovascular disease.
However, thanks to Pauling and his tireless crusade for the innumerable benefits of vitamin C, those who have followed his advice since the 1970s to take high doses of vitamin C for numerous reasons including the prevention of colds and flus have unknowingly been protected from heart disease.
Vitamin C Foundation founder Owen Fonorow, in his 2008 Pauling Therapy Handbookwrites:
"Before long, perhaps after you have heard tales of remarkable case histories of those using Pauling's therapy (maybe perhaps even your own case), you will come to realize that one man can be credited for saving the lives hundreds of thousands of his fellow citizens since 1970.
Linus Pauling was an American hero."
In 2001 Tower Laboratories USA introduced its most powerful mix of Ascorsine-9®, (PRONOUNCED AS-COR-SEEN) which provides every supplement found in the original Heart Technology™formula (Pauling Therapy formula) plus additional nutritional supplements that are recommended by experts in the field of medicine for optimal cardiovascular health
Copy these links into your browser to get the full story from Linus Pauling PH.D and Matthias Rath M.D.
Solution to the Puzzle of Human Cardiovascular Disease
A Unified Theory of Human Cardiovascular Disease